Research Team
CO-PRINICIPAL INVESTIGATORS

Rima Kaddurah-Daouk
Duke University
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Professor in the Departments of Psychiatry and Medicine at Duke University Medical Center. A pioneer in the metabolomics field. She successfully led 5 NIH-funded consortia related to applications of metabolomics in precision medicine including MDPMC, Accelerating Medicines Partnership-AD, Alzheimer Gut Microbiome Initiative; cofounded Metabolomics Society, and Metabolon, a leading biotechnology company specializing in metabolomics. She has extensive experience in assembling teams of researchers to work collaboratively on large scientific projects and has secured over 40 NIH-funded grants over the past decade.

Rob Knight
UC San Diego
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Professor at the University of California San Diego. He is co-founder of the American Gut Project and the Earth Microbiome Project specializing in the development of computational and lab techniques to define human, animal, and environmental microbes.

Sarkis Mazamanian
CalTech
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Professor of Microbiology at the California Institute of Technology. He is a medical microbiologist whose research focuses on the gut-brain axis of communication. His lab was the first to demonstrate that intestinal bacteria direct universal development of the immune system, and control complex behaviors in preclinical models.
Management Team

Edgar Diaz
Duke University

Leyla Schimmel
Duke University
Investigators

Gabi Kastenmüller
Helmholtz Zentrum München
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Acting director of the Institute of Bioinformatics and Systems Biology. Her focus is on human chemical individuality and its effects in health, disease, and treatment, metabolome and genome associations, and bioinformatic tools and databases for metabolomics data analysis.

Matthias Arnold
Helmholtz Zentrum München
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Adjunct Assistant Professor at Duke University. Bioinformatician and lead analyst on metabolomics projects at the Helmholtz Zentrum München. Specializes in metabolomics data and its integration with multi-omics into networks.

Jan Krumsiek
Weill Cornell Medicine
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Assistant Professor of Physiology and Biophysics and Computational Genomics. He develops and applies new analytical methods, including machine learning and bioinformatics, to metabolomics and multi-omic data analysis.

Thomas Hankemeier
Leiden University
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Professor of Analytical BioSciences at the LACDR, PI of the Analytical BioSciences and Metabolomics group, and the Division of Systems Biomedicine and Pharmacology Chair. His research involves innovative analytical tools for metabolomics driven systems biology in personalized health.

Ines Thiele
NUI Galway
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PI of the Molecular Systems Physiology group. She pioneered models and methods allowing large scale computational modelling of the human gut microbiome and its metabolic effect on human metabolism. Her research aims to improve the understanding of how diet influences human health.

Pieter Dorrestein
UC San Diego
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Professor of Pharmacy and Pharmaceutical Sciences, Director of the Collaborative Mass Spectrometry Innovation Center, and Co-Director of the Institute for Metabolomics Medicine. His lab is developing new mass spectrometry-based methods to explore the chemistry of microbes and the human microbiome.

Tatiana Foroud
NCRAD
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Professor of Medical and Molecular Genetics where she chairs the department at Indiana University. She is also a geneticist and leader in dementia research, and the head of the National Centralized Repository for Alzheimer’s Disease and Related Dementias (NCRAD), the NIH funded National Repository for Alzheimer’s Disease and Related Dementias.

Emeran Mayer
UCLA
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Professor of Medicine, Physiology, and Psychiatry. Director of the G. Oppenheimer Center for Neurobiology of Stress and Resilience. He is recognized as a leading investigator of brain gut microbiome interactions in GI disorders, including functional and inflammatory bowel disorders and obesity.

Andy Saykin
Indiana University
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Professor of Radiology; Director of the Indiana ADRC and the Center for Neuroimaging. He uses brain imaging and genomic methods to study mechanisms of memory dysfunction and treatment response in neurological and psychiatric disorders.

Kwangsik Nho
Indiana University
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Associate Professor of Radiology & Imaging Sciences. His research expertise is in the areas of bioinformatics, imaging informatics, and medical informatics. He integrates omics data to perform next generation sequence analysis to gain deeper understanding of the pathogenesis of complex diseases.

Murali Doraiswamy
Duke University
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Professor of Medicine & Psychiatry & Behavioral Sciences; Director of the Neurocognitive Disorders Program and a clinical trials unit involved in the development of many modern diagnostic tests, apps, algorithms, and therapeutics.

Suzanne Craft
Wake Forest
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Professor of Gerontology and Geriatric Medicine. Dr. Craft’s research has centered around Alzheimer’s disease, cognitive disorders, dementia, diet, and insulin resistance. She leads the Wake Forest AD Research Center and the BEAT-AD clinical diet trial which examines the effects of a modified Mediterranean-Ketogenic Diet on AD biomarkers and cognition.

Cornelia van Duijn
Oxford University
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Professor of Epidemiology at Nuffield Department of Population Health and a Fellow of St Cross College, Oxford.Her research at the Oxford Big Data Institute focuses on large scale omics studies of Alzheimer’s Disease and other neurodegenerative disorders.

Robin Voigt-Zuwala
Rush University
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Associate Professor, Department of Internal Medicine. Director of Operations of the Rush Center for Microbiome and Chronobiology Research. She studies the microbiota-gut-brain axis in Alzheimer’s disease, Parkinson’s disease, and post-traumatic stress disorder.

Ali Keshavarzian
Rush University
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Professor, Departments of Internal Medicine, Pharmacology, and Molecular Physiology. Director of the Rush Center for Microbiome and Chronobiology Research and the Institute for Advanced Study of the Gut, Chronobiology & Inflammation. He studies the impact of environmental factors on intestinal barrier function host/microbe interaction that promote intestinal and systemic (gut-derived) inflammation.